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Esophageal squamous cell carcinoma with low mitochondrial copy number has mesenchymal and stem-like characteristics, and contributes to poor prognosis

Alterations in mitochondrial DNA (mtDNA) copy numbers in various human cancers have been studied, but any such changes in esophageal squamous cell carcinoma (ESCC) are not established. In the present study, we investigated the correlation of mtDNA copy number with clinicopathologic features, prognos...

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Detalles Bibliográficos
Autores principales: Masuike, Yasunori, Tanaka, Koji, Makino, Tomoki, Yamasaki, Makoto, Miyazaki, Yasuhiro, Takahashi, Tsuyoshi, Kurokawa, Yukinori, Nakajima, Kiyokazu, Mori, Masaki, Doki, Yuichiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5814088/
https://www.ncbi.nlm.nih.gov/pubmed/29447301
http://dx.doi.org/10.1371/journal.pone.0193159