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Biophysical attributes that affect CaMKII activation deduced with a novel spatial stochastic simulation approach
Calcium/calmodulin-dependent protein kinase II (CaMKII) holoenzymes play a critical role in decoding Ca(2+) signals in neurons. Understanding how this occurs has been the focus of numerous studies including many that use models. However, CaMKII is notoriously difficult to simulate in detail because...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5814094/ https://www.ncbi.nlm.nih.gov/pubmed/29401454 http://dx.doi.org/10.1371/journal.pcbi.1005946 |