Ganglioside GM1 contributes to extracellular/intracellular regulation of insulin resistance, impairment of insulin signaling and down-stream eNOS activation, in human aortic endothelial cells after short- or long-term exposure to TNFα

Vascular insulin resistance induced by inflammatory cytokines leads to the initiation and development of vascular diseases. In humans, circulating TNFα levels are increased during aging, suggesting a correlation between vascular insulin resistance and plasma TNFα levels. Currently, the precise molec...

Descripción completa

Detalles Bibliográficos
Autores principales: Sasaki, Norihiko, Itakura, Yoko, Toyoda, Masashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper: Gerotarget (Focus on Aging)
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5814158/
https://www.ncbi.nlm.nih.gov/pubmed/29464018
http://dx.doi.org/10.18632/oncotarget.23726

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5814158/
https://www.ncbi.nlm.nih.gov/pubmed/29464018
http://dx.doi.org/10.18632/oncotarget.23726

Ejemplares similares