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MMP2-A2M interaction increases ECM accumulation in aged rat kidney and its modulation by calorie restriction
Age-associated renal fibrosis is related with renal function decline during aging. Imbalance between accumulation and degradation of extracellular matrix is key feature of fibrosis. In this study, RNA-sequencing (RNA-Seq) results based on next-generation sequencing (NGS) data were analyzed to identi...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5814160/ https://www.ncbi.nlm.nih.gov/pubmed/29464020 http://dx.doi.org/10.18632/oncotarget.23652 |