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MMP2-A2M interaction increases ECM accumulation in aged rat kidney and its modulation by calorie restriction

Age-associated renal fibrosis is related with renal function decline during aging. Imbalance between accumulation and degradation of extracellular matrix is key feature of fibrosis. In this study, RNA-sequencing (RNA-Seq) results based on next-generation sequencing (NGS) data were analyzed to identi...

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Detalles Bibliográficos
Autores principales: Kim, Kyung Mok, Chung, Ki Wung, Jeong, Hyeong Oh, Lee, Bonggi, Kim, Dae Hyun, Park, June Whoun, Kim, Seong Min, Yu, Byung Pal, Chung, Hae Young
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5814160/
https://www.ncbi.nlm.nih.gov/pubmed/29464020
http://dx.doi.org/10.18632/oncotarget.23652