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Under-expression of CK2β subunit in ccRCC represents a complementary biomarker of p-STAT3 Ser727 that correlates with patient survival

Clear cell renal cell carcinoma (ccRCC) is the most common and aggressive subtype of renal cancer. STAT3 pathway is altered in these tumors and p-STAT3 Ser727 is an independent prognostic factor for ccRCC. Protein kinase CK2 is altered in different types of tumors and overexpression of CK2α is consi...

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Detalles Bibliográficos
Autores principales: Vilardell, Jordi, Alcaraz, Estefania, Sarró, Eduard, Trilla, Enric, Cuadros, Thaïs, de Torres, Inés, Plana, Maria, Ramón y Cajal, Santiago, Pinna, Lorenzo A., Ruzzene, Maria, Morote, Juan, Meseguer, Anna, Itarte, Emilio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5814170/
https://www.ncbi.nlm.nih.gov/pubmed/29464030
http://dx.doi.org/10.18632/oncotarget.23422