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Stroma-derived extracellular vesicles deliver tumor-suppressive miRNAs to pancreatic cancer cells

The biology of tumor-associated stroma (TAS) in pancreatic ductal adenocarcinoma (PDAC) is not well understood. The paradoxical observation that stroma-depletion strategies lead to progression of PDAC reinforced the need to critically evaluate the functional contribution of TAS in the initiation and...

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Detalles Bibliográficos
Autores principales: Han, Song, Gonzalo, David H., Feely, Michael, Rinaldi, Carlos, Belsare, Sayali, Zhai, Haiyan, Kalra, Krishan, Gerber, Michael H., Forsmark, Christopher E., Hughes, Steven J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5814172/
https://www.ncbi.nlm.nih.gov/pubmed/29464032
http://dx.doi.org/10.18632/oncotarget.23532