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Stroma-derived extracellular vesicles deliver tumor-suppressive miRNAs to pancreatic cancer cells
The biology of tumor-associated stroma (TAS) in pancreatic ductal adenocarcinoma (PDAC) is not well understood. The paradoxical observation that stroma-depletion strategies lead to progression of PDAC reinforced the need to critically evaluate the functional contribution of TAS in the initiation and...
Autores principales: | Han, Song, Gonzalo, David H., Feely, Michael, Rinaldi, Carlos, Belsare, Sayali, Zhai, Haiyan, Kalra, Krishan, Gerber, Michael H., Forsmark, Christopher E., Hughes, Steven J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5814172/ https://www.ncbi.nlm.nih.gov/pubmed/29464032 http://dx.doi.org/10.18632/oncotarget.23532 |
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