Activation of Grm1 expression by mutated BRaf (V600E) in vitro and in vivo

Our laboratory previously showed that ectopic expression of Grm1 is sufficient to induce spontaneous melanoma formation with 100% penetrance in transgenic mouse model, TG-3, which harbors wild-type BRaf. Studies identified Grm1 expression in human melanoma cell lines and primary to secondary metasta...

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Detalles Bibliográficos
Autores principales: Chen, Ho-Chung, Sierra, Jairo, Yu, Lumeng Jenny, Cerchio, Robert, Wall, Brian A., Goydos, James, Chen, Suzie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5814180/
https://www.ncbi.nlm.nih.gov/pubmed/29464040
http://dx.doi.org/10.18632/oncotarget.23637

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5814180/
https://www.ncbi.nlm.nih.gov/pubmed/29464040
http://dx.doi.org/10.18632/oncotarget.23637

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