Inhibition of NF-κB prevents the acidic bile-induced oncogenic mRNA phenotype, in human hypopharyngeal cells

Bile-containing gastro-duodenal reflux has been clinically considered an independent risk factor in hypopharyngeal carcinogenesis. We recently showed that the chronic effect of acidic bile, at pH 4.0, selectively induces NF-κB activation and accelerates the transcriptional levels of genes, linked to...

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Detalles Bibliográficos
Autores principales: Vageli, Dimitra P., Doukas, Sotirios G., Sasaki, Clarence T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5814181/
https://www.ncbi.nlm.nih.gov/pubmed/29464041
http://dx.doi.org/10.18632/oncotarget.23143

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5814181/
https://www.ncbi.nlm.nih.gov/pubmed/29464041
http://dx.doi.org/10.18632/oncotarget.23143

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