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Combination of a thioxodihydroquinazolinone with cisplatin eliminates ovarian cancer stem cell-like cells (CSC-LCs) and shows preclinical potential

Cancer stem cell-like cells (CSC-LCs) contribute to drug resistance and recurrence of ovarian cancer. Strategies that can eradicate CSC-LCs are expected to substantially improve the outcome of ovarian cancer treatment. We have previously identified a class of thioxodihydroquinazolinone small molecul...

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Detalles Bibliográficos
Autores principales: Ma, Jing, Salamoun, Joseph, Wipf, Peter, Edwards, Robert, Van Houten, Bennett, Qian, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5814193/
https://www.ncbi.nlm.nih.gov/pubmed/29464053
http://dx.doi.org/10.18632/oncotarget.23679