Intravesicular epidermal growth factor receptor subject to retrograde trafficking drives epidermal growth factor-dependent migration

The Epidermal Growth Factor Receptor (EGFR) is frequently mutated and overexpressed in metastatic cancer. Although EGFR is a transmembrane tyrosine kinase localized to the basolateral membrane in normal epithelium, it is frequently found intracellularly localized in transformed cells. We have previo...

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Detalles Bibliográficos
Autores principales: Maisel, Sabrina, Broka, Derrick, Schroeder, Joyce
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5814225/
https://www.ncbi.nlm.nih.gov/pubmed/29464085
http://dx.doi.org/10.18632/oncotarget.23766

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5814225/
https://www.ncbi.nlm.nih.gov/pubmed/29464085
http://dx.doi.org/10.18632/oncotarget.23766

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