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Intravesicular epidermal growth factor receptor subject to retrograde trafficking drives epidermal growth factor-dependent migration

The Epidermal Growth Factor Receptor (EGFR) is frequently mutated and overexpressed in metastatic cancer. Although EGFR is a transmembrane tyrosine kinase localized to the basolateral membrane in normal epithelium, it is frequently found intracellularly localized in transformed cells. We have previo...

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Detalles Bibliográficos
Autores principales:	Maisel, Sabrina, Broka, Derrick, Schroeder, Joyce
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2017
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5814225/ https://www.ncbi.nlm.nih.gov/pubmed/29464085 http://dx.doi.org/10.18632/oncotarget.23766

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