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The evolutionary pattern of mutations in glioblastoma reveals therapy-mediated selection

Glioblastoma presents as a heterogeneous disease with poor prognosis despite the use of multimodal therapy. Analysis of genomic DNA changes between initial diagnosis and recurrence in response to standard treatment protocols would enhance understanding of disease progression and better inform new tr...

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Detalles Bibliográficos
Autores principales: Muscat, Andrea M., Wong, Nicholas C., Drummond, Katharine J., Algar, Elizabeth M., Khasraw, Mustafa, Verhaak, Roel, Field, Kathryn, Rosenthal, Mark A., Ashley, David M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5814263/
https://www.ncbi.nlm.nih.gov/pubmed/29487696
http://dx.doi.org/10.18632/oncotarget.23541