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The evolutionary pattern of mutations in glioblastoma reveals therapy-mediated selection
Glioblastoma presents as a heterogeneous disease with poor prognosis despite the use of multimodal therapy. Analysis of genomic DNA changes between initial diagnosis and recurrence in response to standard treatment protocols would enhance understanding of disease progression and better inform new tr...
Autores principales: | Muscat, Andrea M., Wong, Nicholas C., Drummond, Katharine J., Algar, Elizabeth M., Khasraw, Mustafa, Verhaak, Roel, Field, Kathryn, Rosenthal, Mark A., Ashley, David M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5814263/ https://www.ncbi.nlm.nih.gov/pubmed/29487696 http://dx.doi.org/10.18632/oncotarget.23541 |
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