SIRT1 increases cardiomyocyte binucleation in the heart development

SIRT1 regulates cell senescence. We investigated a novel role of SIRT1 in the regulation of cardiomyocyte terminal differentiation in the developing heart. Retinoic acid (RA)-induced binucleation of H9c2 cells was associated with increased SIRT1 expression. Inhibition of SIRT1 activity or expression...

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Detalles Bibliográficos
Autores principales: Shin, Alexandra N., Han, Limin, Dasgupta, Chiranjib, Huang, Lei, Yang, Shumei, Zhang, Lubo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5814276/
https://www.ncbi.nlm.nih.gov/pubmed/29487709
http://dx.doi.org/10.18632/oncotarget.23847

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5814276/
https://www.ncbi.nlm.nih.gov/pubmed/29487709
http://dx.doi.org/10.18632/oncotarget.23847

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