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First evidence for a multienzyme complex of lipid biosynthesis pathway enzymes in Cunninghamella bainieri

Malic enzyme (ME) plays a vital role in determining the extent of lipid accumulation in oleaginous fungi being the major provider of NADPH for the activity of fatty acid synthase (FAS). We report here the first direct evidence of the existence of a lipogenic multienzyme complex (the lipid metabolon)...

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Detalles Bibliográficos
Autores principales: Shuib, Shuwahida, Ibrahim, Izyanti, Mackeen, Mukram Mohamed, Ratledge, Colin, Hamid, Aidil Abdul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5814418/
https://www.ncbi.nlm.nih.gov/pubmed/29449592
http://dx.doi.org/10.1038/s41598-018-21452-4