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Optimising the decellularization of human elastic cartilage with trypsin for future use in ear reconstruction

Decellularized scaffolds can induce chondrogenic differentiation of stem cells. This study compares different methods to optimise the decellularization of auricular cartilage. The process consisted of an initial 12 hour dry freeze thaw which froze the cartilage specimens in an empty tube at −20 °C....

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Detalles Bibliográficos
Autores principales: Rahman, Shafiq, Griffin, Michelle, Naik, Anish, Szarko, Matthew, Butler, Peter E. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5814427/
https://www.ncbi.nlm.nih.gov/pubmed/29449572
http://dx.doi.org/10.1038/s41598-018-20592-x