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USP35 regulates mitotic progression by modulating the stability of Aurora B

Although approximately 100 deubiquitinating enzymes (DUBs) are encoded in the human genome, very little is known about the DUBs that function in mitosis. Here, we demonstrate that DUB USP35 functions as a mitotic regulator by controlling the protein levels and downstream signaling of Aurora B and th...

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Detalles Bibliográficos
Autores principales: Park, Jinyoung, Kwon, Mi-Sun, Kim, Eunice EunKyeong, Lee, Hyunsook, Song, Eun Joo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5814453/
https://www.ncbi.nlm.nih.gov/pubmed/29449677
http://dx.doi.org/10.1038/s41467-018-03107-0