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CD1d-dependent immune suppression mediated by regulatory B cells through modulations of iNKT cells

Regulatory B cells (Breg) express high levels of CD1d that presents lipid antigens to invariant natural killer T (iNKT) cells. The function of CD1d in Breg biology and iNKT cell activity during inflammation remains unclear. Here we show, using chimeric mice, cell depletion and adoptive cell transfer...

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Detalles Bibliográficos
Autores principales: Oleinika, K., Rosser, E. C., Matei, D. E., Nistala, K., Bosma, A., Drozdov, I., Mauri, C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5814456/
https://www.ncbi.nlm.nih.gov/pubmed/29449556
http://dx.doi.org/10.1038/s41467-018-02911-y