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Decreased succinate dehydrogenase B in human hepatocellular carcinoma accelerates tumor malignancy by inducing the Warburg effect

Changes in TCA cycle enzymes or respiratory activity are possible mechanisms of aerobic glycolysis that contributes to tumor progression. To clarify whether the decrease of succinate dehydrogenase B (SDHB) alters energy metabolism, induces the Warburg effect and results in tumor malignancy, SDHB exp...

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Detalles Bibliográficos
Autores principales: Tseng, Po-Lin, Wu, Wei-Hsuan, Hu, Tsung-Hui, Chen, Chih-Wei, Cheng, Hung-Chi, Li, Chien-Feng, Tsai, Wen-Hui, Tsai, Hui-Ju, Hsieh, Meng-Che, Chuang, Jiin-Haur, Chang, Wen-Tsan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5814459/
https://www.ncbi.nlm.nih.gov/pubmed/29449614
http://dx.doi.org/10.1038/s41598-018-21361-6