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On the Reproducibility of Label-Free Quantitative Cross-Linking/Mass Spectrometry

Quantitative cross-linking/mass spectrometry (QCLMS) is an emerging approach to study conformational changes of proteins and multi-subunit complexes. Distinguishing protein conformations requires reproducibly identifying and quantifying cross-linked peptides. Here we analyzed the variation between m...

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Detalles Bibliográficos
Autores principales: Müller, Fränze, Fischer, Lutz, Chen, Zhuo Angel, Auchynnikava, Tania, Rappsilber, Juri
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5814520/
https://www.ncbi.nlm.nih.gov/pubmed/29256016
http://dx.doi.org/10.1007/s13361-017-1837-2