Loss of the homeostatic protein BPIFA1, leads to exacerbation of otitis media severity in the Junbo mouse model

Otitis Media (OM) is characterized by epithelial abnormalities and defects in innate immunity in the middle ear (ME). Although, BPIFA1, a member of the BPI fold containing family of putative innate defence proteins is abundantly expressed by the ME epithelium and SNPs in Bpifa1 have been associated...

Descripción completa

Detalles Bibliográficos
Autores principales: Mulay, Apoorva, Hood, Derek W., Williams, Debbie, Russell, Catherine, Brown, Steve D. M., Bingle, Lynne, Cheeseman, Michael, Bingle, Colin D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5814562/
https://www.ncbi.nlm.nih.gov/pubmed/29449589
http://dx.doi.org/10.1038/s41598-018-21166-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5814562/
https://www.ncbi.nlm.nih.gov/pubmed/29449589
http://dx.doi.org/10.1038/s41598-018-21166-7

Ejemplares similares