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Catechol O-methyltransferase (COMT) functional haplotype is associated with recurrence of affective symptoms: A prospective birth cohort study

BACKGROUND: Catechol-O-methyltransferase (COMT) polymorphisms play an essential role in dopamine availability in the brain. However, there has been no study investigating whether a functional four-SNP (rs6269-rs4633-rs4818-rs4680) haplotype is associated with affective symptoms over the life course....

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Detalles Bibliográficos
Autores principales: Koike, Shinsuke, Gaysina, Darya, Jones, Peter B., Wong, Andrew, Richards, Marcus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier/North-Holland Biomedical Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5814675/
https://www.ncbi.nlm.nih.gov/pubmed/29331705
http://dx.doi.org/10.1016/j.jad.2017.12.044