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Dense‐core vesicle biogenesis and exocytosis in neurons lacking chromogranins A and B

Chromogranin A and B (Cgs) are considered to be master regulators of cargo sorting for the regulated secretory pathway (RSP) and dense‐core vesicle (DCV) biogenesis. To test this, we analyzed the release of neuropeptide Y (NPY)‐pHluorin, a live RSP reporter, and the distribution, number, and appeara...

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Detalles Bibliográficos
Autores principales: Dominguez, Natalia, van Weering, Jan R. T., Borges, Ricardo, Toonen, Ruud F. G., Verhage, Matthijs
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5814729/
https://www.ncbi.nlm.nih.gov/pubmed/29178418
http://dx.doi.org/10.1111/jnc.14263