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Molecular profiling and genome‐wide analysis based on somatic copy number alterations in advanced colorectal cancers

To characterize somatic alterations in colorectal cancer (CRC), we conducted a genome‐scale analysis of 106 CRC specimens. We assessed comprehensive somatic copy number alterations (SCNAs) in these CRC specimens. In addition, we examined microsatellite instability (MSI; low and high), genetic mutati...

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Detalles Bibliográficos
Autores principales: Sugai, Tamotsu, Takahashi, Yayoi, Eizuka, Makoto, Sugimoto, Ryo, Fujita, Yasuko, Habano, Wataru, Otsuka, Kouki, Sasaki, Akira, Yamamoto, Eiichiro, Matsumoto, Takayuki, Suzuki, Hiromu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5814737/
https://www.ncbi.nlm.nih.gov/pubmed/29230882
http://dx.doi.org/10.1002/mc.22769