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netSmooth: Network-smoothing based imputation for single cell RNA-seq
Single cell RNA-seq (scRNA-seq) experiments suffer from a range of characteristic technical biases, such as dropouts (zero or near zero counts) and high variance. Current analysis methods rely on imputing missing values by various means of local averaging or regression, often amplifying biases inher...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
F1000 Research Limited
2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5814748/ https://www.ncbi.nlm.nih.gov/pubmed/29511531 http://dx.doi.org/10.12688/f1000research.13511.3 |