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Objective, Quantitative, Data-Driven Assessment of Chemical Probes

Chemical probes are essential tools for understanding biological systems and for target validation, yet selecting probes for biomedical research is rarely based on objective assessment of all potential compounds. Here, we describe the Probe Miner: Chemical Probes Objective Assessment resource, capit...

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Detalles Bibliográficos
Autores principales: Antolin, Albert A., Tym, Joseph E., Komianou, Angeliki, Collins, Ian, Workman, Paul, Al-Lazikani, Bissan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5814752/
https://www.ncbi.nlm.nih.gov/pubmed/29249694
http://dx.doi.org/10.1016/j.chembiol.2017.11.004