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Nonsense-mediated mRNA decay: a ‘nonsense’ pathway makes sense in stem cell biology

Nonsense-mediated mRNA decay (NMD) is a highly conserved post-transcriptional regulatory mechanism of gene expression in eukaryotes. Originally, NMD was identified as an RNA surveillance machinery in degrading ‘aberrant’ mRNA species with premature termination codons. Recent studies indicate that NM...

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Detalles Bibliográficos
Autores principales: Han, Xin, Wei, Yanling, Wang, Hua, Wang, Feilong, Ju, Zhenyu, Li, Tangliang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5814811/
https://www.ncbi.nlm.nih.gov/pubmed/29272451
http://dx.doi.org/10.1093/nar/gkx1272