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Nonsense-mediated mRNA decay: a ‘nonsense’ pathway makes sense in stem cell biology
Nonsense-mediated mRNA decay (NMD) is a highly conserved post-transcriptional regulatory mechanism of gene expression in eukaryotes. Originally, NMD was identified as an RNA surveillance machinery in degrading ‘aberrant’ mRNA species with premature termination codons. Recent studies indicate that NM...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5814811/ https://www.ncbi.nlm.nih.gov/pubmed/29272451 http://dx.doi.org/10.1093/nar/gkx1272 |