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Nuclear mRNA degradation tunes the gain of the unfolded protein response in Saccharomyces cerevisiae
Unfolded protein response (UPR) is triggered by the accumulation of unfolded proteins in the endoplasmic reticulum (ER), which is accomplished by a dramatic induction of genes encoding ER chaperones. Activation of these genes involves their rapid transcription by Hac1p, encoded by the HAC1 precursor...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5814838/ https://www.ncbi.nlm.nih.gov/pubmed/29165698 http://dx.doi.org/10.1093/nar/gkx1160 |