Cargando…

Nuclear mRNA degradation tunes the gain of the unfolded protein response in Saccharomyces cerevisiae

Unfolded protein response (UPR) is triggered by the accumulation of unfolded proteins in the endoplasmic reticulum (ER), which is accomplished by a dramatic induction of genes encoding ER chaperones. Activation of these genes involves their rapid transcription by Hac1p, encoded by the HAC1 precursor...

Descripción completa

Detalles Bibliográficos
Autores principales: Sarkar, Debasish, Paira, Sunirmal, Das, Biswadip
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5814838/
https://www.ncbi.nlm.nih.gov/pubmed/29165698
http://dx.doi.org/10.1093/nar/gkx1160