Pharmacokinetics of Diclofenac and Hydroxypropyl‐β‐Cyclodextrin (HPβCD) Following Administration of Injectable HPβCD‐Diclofenac in Subjects With Mild to Moderate Renal Insufficiency or Mild Hepatic Impairment

Given their established analgesic properties, nonsteroidal anti‐inflammatory drugs (NSAIDs) represent an important postoperative pain management option. This study investigated: (1) the effects of mild or moderate renal insufficiency and mild hepatic impairment on the pharmacokinetics (PK) of diclof...

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Detalles Bibliográficos
Autores principales: Hamilton, Douglas A., Ernst, Cynthia C., Kramer, William G., Madden, Donna, Lang, Eric, Liao, Edward, Lacouture, Peter G., Ramaiya, Atulkumar, Carr, Daniel B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5814843/
https://www.ncbi.nlm.nih.gov/pubmed/29197175
http://dx.doi.org/10.1002/cpdd.417

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5814843/
https://www.ncbi.nlm.nih.gov/pubmed/29197175
http://dx.doi.org/10.1002/cpdd.417

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