Oligonucleotides with Cationic Backbone and Their Hybridization with DNA: Interplay of Base Pairing and Electrostatic Attraction

Non‐natural oligonucleotides represent important (bio)chemical tools and potential therapeutic agents. Backbone modifications altering hybridization properties and biostability can provide useful analogues. Here, we employ an artificial nucleosyl amino acid (NAA) motif for the synthesis of oligonucl...

Descripción completa

Detalles Bibliográficos
Autores principales: Schmidtgall, Boris, Kuepper, Arne, Meng, Melissa, Grossmann, Tom N., Ducho, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Full Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5814856/
https://www.ncbi.nlm.nih.gov/pubmed/29048135
http://dx.doi.org/10.1002/chem.201704338

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5814856/
https://www.ncbi.nlm.nih.gov/pubmed/29048135
http://dx.doi.org/10.1002/chem.201704338

Ejemplares similares