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Accuracy of genetic code translation and its orthogonal corruption by aminoglycosides and Mg(2+) ions
We studied the effects of aminoglycosides and changing Mg(2+) ion concentration on the accuracy of initial codon selection by aminoacyl-tRNA in ternary complex with elongation factor Tu and GTP (T(3)) on mRNA programmed ribosomes. Aminoglycosides decrease the accuracy by changing the equilibrium con...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Oxford University Press
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5814885/ https://www.ncbi.nlm.nih.gov/pubmed/29267976 http://dx.doi.org/10.1093/nar/gkx1256 |