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Prolyl isomerization of the CENP-A N-terminus regulates centromeric integrity in fission yeast
Centromeric identity and chromosome segregation are determined by the precise centromeric targeting of CENP-A, the centromere-specific histone H3 variant. The significance of the amino-terminal domain (NTD) of CENP-A in this process remains unclear. Here, we assessed the functional significance of e...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5814953/ https://www.ncbi.nlm.nih.gov/pubmed/29194511 http://dx.doi.org/10.1093/nar/gkx1180 |