Prolyl isomerization of the CENP-A N-terminus regulates centromeric integrity in fission yeast

Centromeric identity and chromosome segregation are determined by the precise centromeric targeting of CENP-A, the centromere-specific histone H3 variant. The significance of the amino-terminal domain (NTD) of CENP-A in this process remains unclear. Here, we assessed the functional significance of e...

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Detalles Bibliográficos
Autores principales: Tan, Hwei Ling, Lim, Kim Kiat, Yang, Qiaoyun, Fan, Jing-Song, Sayed, Ahmed Mahmoud Mohammed, Low, Liy Sim, Ren, Bingbing, Lim, Teck Kwang, Lin, Qingsong, Mok, Yu-Keung, Liou, Yih-Cherng, Chen, Ee Sin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Gene regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5814953/
https://www.ncbi.nlm.nih.gov/pubmed/29194511
http://dx.doi.org/10.1093/nar/gkx1180

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