Transcriptional Regulation of Telomeric Expression Sites and Antigenic Variation in Trypanosomes

INTRODUCTION: Trypanosoma brucei uses antigenic variation to evade the host antibody clearance by periodically changing its Variant Surface Glycoprotein (VSGs) coat. T. brucei encode over 2,500 VSG genes and pseudogenes, however they transcribe only one VSG gene at time from one of the 20 telomeric...

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Detalles Bibliográficos
Autores principales: Cestari, Igor, Stuart, Ken
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bentham Science Publishers 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5814960/
https://www.ncbi.nlm.nih.gov/pubmed/29491740
http://dx.doi.org/10.2174/1389202918666170911161831

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5814960/
https://www.ncbi.nlm.nih.gov/pubmed/29491740
http://dx.doi.org/10.2174/1389202918666170911161831

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