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Transcriptional Regulation of Telomeric Expression Sites and Antigenic Variation in Trypanosomes
INTRODUCTION: Trypanosoma brucei uses antigenic variation to evade the host antibody clearance by periodically changing its Variant Surface Glycoprotein (VSGs) coat. T. brucei encode over 2,500 VSG genes and pseudogenes, however they transcribe only one VSG gene at time from one of the 20 telomeric...
Autores principales: | Cestari, Igor, Stuart, Ken |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Bentham Science Publishers
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5814960/ https://www.ncbi.nlm.nih.gov/pubmed/29491740 http://dx.doi.org/10.2174/1389202918666170911161831 |
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