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TWJ-Screen: an isothermal screening assay to assess ligand/DNA junction interactions in vitro

The quest for chemicals able to operate at selected genomic loci in a spatiotemporally controlled manner is desirable to create manageable DNA damages. Mounting evidence now shows that alternative DNA structures, including G-quadruplexes and branched DNA (or DNA junctions), might hamper proper progr...

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Detalles Bibliográficos
Autores principales: Guyon, Ludivine, Pirrotta, Marc, Duskova, Katerina, Granzhan, Anton, Teulade-Fichou, Marie-Paule, Monchaud, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5815093/
https://www.ncbi.nlm.nih.gov/pubmed/29149299
http://dx.doi.org/10.1093/nar/gkx1118