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TWJ-Screen: an isothermal screening assay to assess ligand/DNA junction interactions in vitro
The quest for chemicals able to operate at selected genomic loci in a spatiotemporally controlled manner is desirable to create manageable DNA damages. Mounting evidence now shows that alternative DNA structures, including G-quadruplexes and branched DNA (or DNA junctions), might hamper proper progr...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5815093/ https://www.ncbi.nlm.nih.gov/pubmed/29149299 http://dx.doi.org/10.1093/nar/gkx1118 |