Dynamic m(6)A modification regulates local translation of mRNA in axons

N (6)-methyladenosine (m(6)A) is a reversible modification in mRNA and has been shown to regulate processing, translation and decay of mRNA. However, the roles of m(6)A modification in neuronal development are still not known. Here, we found that the m(6)A eraser FTO is enriched in axons and can be...

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Detalles Bibliográficos
Autores principales: Yu, Jun, Chen, Mengxian, Huang, Haijiao, Zhu, Junda, Song, Huixue, Zhu, Jian, Park, Jaewon, Ji, Sheng-Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
RNA and RNA-protein complexes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5815124/
https://www.ncbi.nlm.nih.gov/pubmed/29186567
http://dx.doi.org/10.1093/nar/gkx1182

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5815124/
https://www.ncbi.nlm.nih.gov/pubmed/29186567
http://dx.doi.org/10.1093/nar/gkx1182

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