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Derivative-free neural network for optimizing the scoring functions associated with dynamic programming of pairwise-profile alignment
BACKGROUND: A profile-comparison method with position-specific scoring matrix (PSSM) is among the most accurate alignment methods. Currently, cosine similarity and correlation coefficients are used as scoring functions of dynamic programming to calculate similarity between PSSMs. However, it is uncl...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5815186/ https://www.ncbi.nlm.nih.gov/pubmed/29467815 http://dx.doi.org/10.1186/s13015-018-0123-6 |