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Exosomes taken up by neurons hijack the endosomal pathway to spread to interconnected neurons
In Alzheimer disease and related disorders, the microtubule-associated protein tau aggregates and forms cytoplasmic lesions that impair neuronal physiology at many levels. In addition to affecting the host neuron, tau aggregates also spread to neighboring, recipient cells where the misfolded tau agg...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5815204/ https://www.ncbi.nlm.nih.gov/pubmed/29448966 http://dx.doi.org/10.1186/s40478-018-0514-4 |