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Chitinase-3-like 1 is a biomarker of acute kidney injury and mortality in paediatric severe malaria

BACKGROUND: Chitinase-3-like 1 (CHI3L1) is a glycoprotein elevated in paediatric severe malaria, and an emerging urinary biomarker of acute kidney injury (AKI). Based on the hypothesis that elevated CHI3L1 levels in malaria are associated with disease severity, the relationship between plasma CHI3L1...

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Detalles Bibliográficos
Autores principales: Conroy, Andrea L., Hawkes, Michael T., Elphinstone, Robyn, Opoka, Robert O., Namasopo, Sophie, Miller, Christopher, John, Chandy C., Kain, Kevin C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5815237/
https://www.ncbi.nlm.nih.gov/pubmed/29448936
http://dx.doi.org/10.1186/s12936-018-2225-5