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Double-negative (CD27(−)IgD(−)) B cells are expanded in NSCLC and inversely correlate with affinity-matured B cell populations

BACKGROUND: The presence of B cells in early stage non-small cell lung cancer (NSCLC) is associated with longer survival, however, the role these cells play in the generation and maintenance of anti-tumor immunity is unclear. B cells differentiate into a variety of subsets with differing characteris...

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Detalles Bibliográficos
Autores principales: Centuori, Sara M., Gomes, Cecil J., Kim, Samuel S., Putnam, Charles W., Larsen, Brandon T., Garland, Linda L., Mount, David W., Martinez, Jesse D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5815250/
https://www.ncbi.nlm.nih.gov/pubmed/29448960
http://dx.doi.org/10.1186/s12967-018-1404-z