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Double-negative (CD27(−)IgD(−)) B cells are expanded in NSCLC and inversely correlate with affinity-matured B cell populations
BACKGROUND: The presence of B cells in early stage non-small cell lung cancer (NSCLC) is associated with longer survival, however, the role these cells play in the generation and maintenance of anti-tumor immunity is unclear. B cells differentiate into a variety of subsets with differing characteris...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5815250/ https://www.ncbi.nlm.nih.gov/pubmed/29448960 http://dx.doi.org/10.1186/s12967-018-1404-z |