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Human periodontal ligament stem cells secretome from multiple sclerosis patients suppresses NALP3 inflammasome activation in experimental autoimmune encephalomyelitis

Research in recent years has largely explored the immunomodulatory effects of mesenchymal stem cells (MSCs) and their secretory products, called “secretome,” in the treatment of neuroinflammatory diseases. Here, we examined whether such immunosuppressive effects might be elicited due to inflammasome...

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Detalles Bibliográficos
Autores principales: Soundara Rajan, Thangavelu, Giacoppo, Sabrina, Diomede, Francesca, Bramanti, Placido, Trubiani, Oriana, Mazzon, Emanuela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5815262/
https://www.ncbi.nlm.nih.gov/pubmed/28764573
http://dx.doi.org/10.1177/0394632017722332