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Effects of osmolytes and macromolecular crowders on stable GAAA tetraloops and their preference for a CG closing base pair

Osmolytes and macromolecular crowders have the potential to influence the stability of secondary structure motifs and alter preferences for conserved nucleic acid sequences in vivo. To further understand the cellular function of RNA we observed the effects of a model osmolyte, polyethylene glycol (P...

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Detalles Bibliográficos
Autores principales: Leonard, Kaethe N., Blose, Joshua M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5815330/
https://www.ncbi.nlm.nih.gov/pubmed/29456882
http://dx.doi.org/10.7717/peerj.4236