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The Stress-Induced Transcription Factor NR4A1 Adjusts Mitochondrial Function and Synapse Number in Prefrontal Cortex

The energetic costs of behavioral chronic stress are unlikely to be sustainable without neuronal plasticity. Mitochondria have the capacity to handle synaptic activity up to a limit before energetic depletion occurs. Protective mechanisms driven by the induction of neuronal genes likely evolved to b...

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Detalles Bibliográficos
Autores principales: Jeanneteau, Freddy, Barrère, Christian, Vos, Mariska, De Vries, Carlie J.M., Rouillard, Claude, Levesque, Daniel, Dromard, Yann, Moisan, Marie-Pierre, Duric, Vanja, Franklin, Tina C., Duman, Ronald S., Lewis, David A., Ginsberg, Stephen D., Arango-Lievano, Margarita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for Neuroscience 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5815341/
https://www.ncbi.nlm.nih.gov/pubmed/29295823
http://dx.doi.org/10.1523/JNEUROSCI.2793-17.2017