Viral unmasking of cellular 5S rRNA pseudogene transcripts induces RIG-I mediated immunity

The sensor retinoic acid-inducible gene-I (RIG-I) detects double-stranded RNA derived from RNA viruses. Although RIG-I is also known to play a role in the antiviral response to DNA viruses, physiological RNA species recognized by RIG-I during DNA virus infection are largely unknown. Using next-gener...

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Detalles Bibliográficos
Autores principales: Chiang, Jessica J., Sparrer, Konstantin M.J., van Gent, Michiel, Lässig, Charlotte, Huang, Teng, Osterrieder, Nikolaus, Hopfner, Karl-Peter, Gack, Michaela U.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5815369/
https://www.ncbi.nlm.nih.gov/pubmed/29180807
http://dx.doi.org/10.1038/s41590-017-0005-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5815369/
https://www.ncbi.nlm.nih.gov/pubmed/29180807
http://dx.doi.org/10.1038/s41590-017-0005-y

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