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Viral unmasking of cellular 5S rRNA pseudogene transcripts induces RIG-I mediated immunity
The sensor retinoic acid-inducible gene-I (RIG-I) detects double-stranded RNA derived from RNA viruses. Although RIG-I is also known to play a role in the antiviral response to DNA viruses, physiological RNA species recognized by RIG-I during DNA virus infection are largely unknown. Using next-gener...
Autores principales: | Chiang, Jessica J., Sparrer, Konstantin M.J., van Gent, Michiel, Lässig, Charlotte, Huang, Teng, Osterrieder, Nikolaus, Hopfner, Karl-Peter, Gack, Michaela U. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5815369/ https://www.ncbi.nlm.nih.gov/pubmed/29180807 http://dx.doi.org/10.1038/s41590-017-0005-y |
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