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Cholesterol-Binding Sites in GIRK Channels: The Devil is in the Details

In recent years, it has become evident that cholesterol plays a direct role in the modulation of a variety of ion channels. In most cases, cholesterol downregulates channel activity. In contrast, our earlier studies have demonstrated that atrial G protein inwardly rectifying potassium (GIRK) channel...

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Detalles Bibliográficos
Autor principal: Rosenhouse-Dantsker, Avia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5815411/
https://www.ncbi.nlm.nih.gov/pubmed/29467578
http://dx.doi.org/10.1177/1178635317754071